Pyrrolo[2,3-d]pyrimidin-4-ol(CAS#3680-71-5)
| Hazard Symbols | Xi - Irritant |
| Risk Codes | R36 - Irritating to the eyes R43 - May cause sensitization by skin contact |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37 - Wear suitable protective clothing and gloves. |
| WGK Germany | 3 |
| RTECS | UY9440000 |
| HS Code | 29335990 |
| Hazard Class | IRRITANT |
Introduction
4-Hydroxypyrrolo[2,3-d]pyrimidine (4-HO-DMT) is an organic compound, also known as psilocin or psilotsin. It is a natural hormone found in cannabis-like herbs and a potent hallucinogen.Quality:4-Hydroxypyrrolo[2,3-d]pyrimidine is a colorless crystal or powder. It is stable at room temperature. The compound is unstable in moist air and oxidizes easily.Use:4-Hydroxypyrrolo[2,3-d]pyrimidine has a wide range of applications in medical and botanical research. It is used as a tool to study neurochemistry, neurobiology, and psychology. It is also a very potent hallucinogen, which may produce intense visual and sensory hallucinations.Method:4-Hydroxypyrrolo[2,3-d]pyrimidine can be extracted or synthesized from natural sources. Extraction from natural sources requires the use of chemical separation and purification techniques. The synthesis method involves a multi-step chemical synthesis reaction.Safety Information:4-Hydroxypyrrolo[2,3-d]pyrimidine is a controlled substance, and its legality and safety vary from region to region. It belongs to the category of very strong psychoactive substances and should be used with caution. Excessive or inappropriate use can lead to serious mental and mental health problems. Anyone who uses the compound should be prepared for possible adverse effects and ensure that it is used in a legal and safe environment. The relevant laboratory safety regulations and personal protective measures must be followed when handling this compound.
Application
Pyrrolo[2,3-d]pyrimidin-4-ol (CAS 3680-71-5) is a versatile heterocyclic scaffold widely used as a purine analog in pharmaceutical research and development. It serves as a key intermediate for the synthesis of various bioactive compounds, including antiviral, anticancer, and anti-inflammatory agents. This compound is particularly valuable in the development of kinase inhibitors, such as Janus kinase (JAK) inhibitors for rheumatoid arthritis and Bruton’s tyrosine kinase (BTK) inhibitors for B-cell malignancies. Its structure allows for diverse functionalization at multiple positions, enabling the construction of focused libraries for drug discovery. In medicinal chemistry, it is utilized to mimic natural nucleobases, facilitating the design of nucleoside analogs and other therapeutics. Xinchem offers custom synthesis, custom chemical synthesis, and contract manufacturing of high-purity pyrrolo[2,3-d]pyrimidin-4-ol with flexible scaling from R&D to commercial tons. Contact us today for a competitive quote and reliable global supply.

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