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5-HYDROXY-3-METHYLINDOLE(CAS#1125-40-2)

Chemical Property:

Molecular Formula C9H9NO
Molar Mass 147.17
Density 1.262
Melting Point 114-115℃
Boling Point 344.8±22.0 °C(Predicted)
pKa 10.17±0.40(Predicted)
Storage Condition under inert gas (nitrogen or Argon) at 2-8°C

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Introduction

Its properties are white to pale yellow crystalline powder, soluble in hot ethanol and insoluble in water. It can be used as a fluorescent indicator, antioxidant, reducing agent, etc. The preparation method is usually synthesized by synthesizing organic synthesis route.It can be irritating to the skin and eyes, and it is necessary to wear appropriate protective gear and avoid direct contact when operating. It should be used in a well-ventilated area to avoid inhaling its dust. When disposing of waste, it should be properly disposed of in accordance with local regulations to avoid pollution to the environment.

Application
5-Hydroxy-3-methylindole (CAS 1125-40-2) is a naturally occurring indole derivative and a key precursor in the biosynthesis of melatonin, the hormone that regulates circadian rhythms. As an antioxidant, it scavenges free radicals and protects cells from oxidative stress. In pharmaceutical research, this compound is used to synthesize melatonin analogs, serotonin receptor modulators, and neuroprotective agents for treating sleep disorders, depression, and neurodegenerative diseases such as Parkinson's and Alzheimer's. In the nutraceutical industry, it serves as an intermediate for melatonin-based dietary supplements supporting sleep and immune health. In cosmetics, its antioxidant properties are leveraged in anti-aging formulations to reduce oxidative damage and improve skin resilience. Additionally, it functions as a building block for fine chemicals and heterocyclic compounds. Xinchem offers custom synthesis, custom chemical synthesis, and contract manufacturing of high-purity 5-hydroxy-3-methylindole with flexible scaling from R&D to commercial tons. Contact us today for a competitive quote and reliable global supply.


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