5-METHYLPYRIDAZIN-3-AMINE(CAS#144294-43-9)
Introduction
5-METHYLPYRIDAZIN-3-AMINE is an organic compound.Quality:5-Methylpyridazine-3-amine is a colorless to pale yellow crystalline or crystalline powder. It is soluble in some organic solvents such as alcohols and ethers, but it is less soluble in water.Uses: It can also be used as a raw material for dyes and pigments.Method:The preparation of 5-methylpyridazine-3-amine is usually carried out by chemical synthesis. A common approach is to add the appropriate functional group to the pyridazine backbone and further modify and functionalize it to obtain the compound of interest.Safety Information:Data on the specific toxicity and hazard of 5-methylpyridazine-3-amine are limited. When using and handling this compound, general laboratory safety practices should be followed, including wearing appropriate personal protective equipment (such as gloves, goggles, and lab coats), practicing good ventilation, and avoiding contact with skin, eyes, and nose and mouth. If necessary, it should be done under the guidance of a chemical professional.
Application
5-Methylpyridazin-3-amine (CAS 144294-43-9) is a versatile heterocyclic building block widely used in medicinal chemistry and pharmaceutical research. The pyridazine core with an amino group at position 3 and a methyl group at position 5 allows diverse functionalization through amide coupling, alkylation, and cross-coupling reactions (Suzuki-Miyaura, Buchwald-Hartwig). This scaffold serves as a key intermediate for the synthesis of kinase inhibitors targeting cancer, inflammation, and autoimmune diseases (e.g., JAK, BTK, CDK inhibitors). It is also utilized in the development of antiviral, antibacterial, and antifungal agents. The methyl group enhances metabolic stability and lipophilicity, while the primary amine provides a handle for rapid structure-activity relationship (SAR) studies. High purity ensures reproducible results in high-throughput screening and scalable GMP manufacturing. Xinchem offers custom synthesis, custom chemical synthesis, and contract manufacturing of 5-methylpyridazin-3-amine with flexible scaling from R&D to commercial tons. Contact us today for a competitive quote and reliable global supply.
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