5-BROMO-3-METHYL-1H-PYRAZOLO[3,4-B]PYRIDINE(CAS#885223-65-4)

Introduction

The following is information about the properties, uses, preparation methods and safety of this compound:Quality:- Appearance: This compound may be a white to light yellow crystalline solid.- Solubility: Soluble in some organic solvents, such as dimethyl iazure.Use:- Due to its specific structure, 5-bromo-3-methyl-1H-pyrazolo[3,4-B]pyridine may be used as an intermediate in organic synthesis and may be used in the preparation of more complex organic compounds.Method:- Typically, this compound can be prepared by synthesizing an appropriate starting material through a series of organic synthesis reactions.Safety Information:- Without specific safety data available, this compound should be considered toxic and harmful. Relevant safety procedures such as wearing protective gloves and glasses should be followed when handling. Direct contact with the skin and inhalation of its vapors should be avoided during use.

Application
5-Bromo-3-methyl-1H-pyrazolo[3,4-b]pyridine (CAS 885223-65-4) is a functionalized heterocyclic building block featuring a methyl group at the 3-position and a bromine at the 5-position on the pyrazolo[3,4-b]pyridine core. This compound serves as a valuable scaffold in medicinal chemistry and drug discovery, particularly for the development of kinase inhibitors targeting cancer, inflammatory diseases, and autoimmune disorders. The bromine atom enables cross-coupling reactions (Suzuki, Buchwald-Hartwig, Sonogashira) for introducing diverse aryl, heteroaryl, or alkyl substituents. The methyl group modulates lipophilicity and metabolic stability, while the NH group allows further alkylation or acylation. As a purine bioisostere, it facilitates structure-activity relationship (SAR) studies and the construction of focused compound libraries. High purity ensures reproducible biological assay results. Xinchem offers custom synthesis, custom chemical synthesis, and contract manufacturing of this key intermediate with flexible scaling from R&D to commercial tons. Contact us today for a competitive quote and reliable global supply.